Dietary Antigen Specific IgA
Dunwoody Labs Dietary Antigen Specific salivary secretory IgA (sIgA) test uses saliva to assess what foods may be triggering a reaction. sIgA may be one of the earliest responses to food and is influential in directing the entire immune response. Understanding which foods create inflammation in a patient is critical to moving them forward to optimal wellness.
Secretory IgA (sIgA) is the dominant immunoglobulin secreted across the mucosal surfaces, making up a large portion of our immune system, and is often described as our first line of defence against microbial invasion. It is critical in developing immune tolerance and serves to influence other branches of the immune system such as IgG and IgE. However, just like IgE and IgG, an IgA response can become confused and begin reacting to foods. When sIgA increases to specific foods, levels may rise initially, and it can be associated with gut-based inflammation.
A saliva sample provides a non-invasive medium to check for responses to specific foods. This can also be a useful follow-up profile to a stool profile that may show raised sIgA but does not report a bacterial or viral trigger.