CD57 CD3 Profile
CD57+/CD3- absolute cell count
CD57+/CD3- cells are a subset of NK cells. Their exact function is not well understood but differentiates them from CD56+ NK cells. The absolute number of CD57+/CD3- cells is low in patients suffering from chronic Lyme disease [Stricker et al. 2001]. Patients with very low CD57 have significantly more co-infections and persistent immunologic defects than patients with higher counts. In patients that respond to antibiotic therapy, the number of cells come back to normal. Therefore, this is a useful marker to follow the effect of therapy.