Invivo Clinical provides diagnostic services from RealTimeLaboratories, Inc. (RTL). RealTime Labs are a Dallas-based clinical laboratory, specialising in the detection of mycotoxins (the toxins produced my molds) in the human body. RTL carries both CAP and CLIA certifications, the highest accreditations available to medical testing facilities.
What are Mycotoxins?
There are estimated to be over 50,000 different species of mold, but only about 200 present serious health risks to humans or animals. These harmful species are referred to as toxic mold and are potentially hazardous because they can produce toxins known as mycotoxins.
The mycotoxins discussed here are the Trichothecenes, Aflatoxins, Ochratoxins, Gliotoxin, Chaetoglobosins and Sterigmatocystin. Where conditions are right, fungi proliferate into colonies and mycotoxin levels become high. Toxins vary greatly in their severity: some fungi produce severe toxins only at specific levels of moisture, temperature or oxygen in the air; some toxins are lethal; some cause identifiable diseases or health problems; some weaken the immune system without producing symptoms specific to that toxin; some act as allergens or irritants, and some have no known effect on humans.
Trichothecenes are evaluated by using Enzyme-Linked ImmunoSorbant Assay (ELISA). The test at RTL has been validated as a qualitative test. Thus, RTL reports whether tricothecenes are PRESENT or NOT PRESENT.
Aflatoxins are evaluated using
ImmunoSorbant Columns containing antibodies to the group of aflatoxins (B1, B2,
G1, and G2). Results are reported as PRESENT or NOT PRESENT.
Ochratoxin A is evaluated using immunoSorbant Columns containing antibodies to the Ochratoxin A. Results are reported as PRESENT or NOT PRESENT.
Health Problems Associated With Molds and Mycotoxins
Mycotoxins are well documented for their toxic effects on the human cell, causing a number of problems in normal cell function and association with a wide variety of clinical symptoms and diseases:
- Kidney Toxicity
- Immune Suppression
- Chronic Fatigue Syndrome
- Acute Pulmonary Haemorrhage
- Aplastic Anaemia
- Birth Defects
Who Should Be Tested?
In light of the above, if you believe someone's health may be compromised by exposure to mold, it may be worth having the person tested using the RealTime Lab Mycotoxin Panel.
How Are They Tested?
The Mycotoxin Panel is a urinary sample, but sputum, nasal washes and tissues biopsy specimens have also been validated.
Testing is done using competitive ELISA, a very sensitive detection method using antibodies prepared against mycotoxins. RealTime Labs has been granted a U.S. patent for its macrocyclic trichothecene test. All mycotoxin testing results are displayed in an easy-to-understand numeric format, showing detection levels in ppb as standardized by the FDA, WHO, CDC and Food Industry for clinical use. Results also tell if the test was positive, negative or equivocal, along with ranges of detection for each.
Results are typically available within 7 business days.
Click to download research papers Dr Hooper (RealTime Labs) has published on mycotoxins: